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| 产地 | France |
| 品牌 | abinscience |
| 保存条件 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
| 货号 | AV974024 |
| 用途 | 供科研使用 |
| 应用范围 | ELISA |
| 抗原来源 | Rabbit |
| 保质期 | 1 year |
| 抗体名 | Anti-Avelumab Polyclonal Antibody |
| 是否单克隆 | 否 |
| 克隆性 | 是 |
| 靶点 | Rabbit polyclonal to Bavencio. |
| 适应物种 | |
| 形态 | Liquid |
| 宿主 | Rabbit |
| 标记物 | |
| 包装规格 | 50ug |
| 亚型 | IgG |
| 标识物 | |
| 浓度 | 95% |
| 免疫原 | |
| 是否进口 | 否 |
| Product name | Anti-Avelumab Polyclonal Antibody |
|---|---|
| Catalog No. | AV974024 |
| Host species | Rabbit |
| Specificity | The product is specific for Avelumab. This antibody serves as an excellent positive control for Avelumab immunogenicity (ADA) assays. |
| Conjugation | \ |
| Species reactivity | \ |
| Immunogen | Avelumab |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Purity | \ |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | ELISA |
| Target | Rabbit polyclonal to Bavencio. |
| Purification | Purified by antigen affinity column. |
| Accession | CAS: 1537032-82-8 |
| Stability and Storage | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
| Background | Avelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as |
| Alternative Names | \ |
| Clone ID | \ |
| Species | \ |
| Note | Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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