链接：https://www.abinscience.cn/product/78/25060.html
名称：Yersinia enterocolitica ail/Attachment invasion locus Recombinant Protein (N-His-SUMO)
货号：JN905012
表达系统：E. coli
Accession号：P16454
蛋白长度：Ala24-Phe178
应用：ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属：Yersinia enterocolitica
性质：Recombinant
内毒素水平：Please contact with the lab for this information.
纯度：>90% as determined by SDS-PAGE.
预测分子量：29.64 kDa
状态：Lyophilized
用途范围：仅用于科研
储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
产品介绍：2026年伊尔库茨克抗鼠疫所事件引发耶尔森菌属关注，除鼠疫菌外，小肠结肠炎耶尔森菌的侵袭相关毒力因子同样值得研究。JN905012 重组 Ail 蛋白聚焦外膜侵袭位点与血清抵抗机制，适用于粘附侵袭研究、抗体开发及致病株鉴定。
Yersinia enterocolitica ail/Attachment invasion locus Recombinant Protein (N-His-SUMO)｜JN905012 是艾必赛生物（abinScience）推出的重组靶标蛋白（原核表达系统），对应小肠结肠炎耶尔森菌的 ail（Attachment invasion locus）外膜蛋白，可作为耶尔森菌黏附/侵袭相关 ELISA、WB、SDS-PAGE 及抗血清/多克隆抗体筛选的抗原对照或标准品。该蛋白选取 Ala24–Phe178 区，带 N 端 His-SUMO 标签，在 E. coli 中表达，纯度 >90%（SDS-PAGE），以冻干粉形式保存（冻干前缓冲液为 PBS pH 7.4，含海藻糖、甘露醇等保护剂）；复溶后短期 2–8°C（≤1 周），长期 -20°C～-80°C 分装避反复冻融（自收货日起 ≤12 个月）。（RUO，仅限科研/非临床用途）
ail 蛋白是致病性耶尔森菌属表面的小型外膜 β-桶蛋白，主要介导细菌对宿主细胞的附着与侵袭，并通过招募 factor H、C4BP 等补体调节蛋白增强血清补体抵抗；在 Y. pestis 中还与 III 型分泌系统（T3SS）Yop 效应蛋白递送相关。 因此 ail 是耶尔森菌毒力机制、抗黏附药物筛选及血清学检测开发中的常用靶标抗原，JN905012 适合作为阳性对照蛋白用于抗体配对、免疫原性评估或重组蛋白功能实验
产品购买联系方式：027-87433958/17302791434
邮箱：info@abinscience.com
参考文献：
The Gene Ail for the Attachment-Invasion Locus Protein of Yersinia enterocolitica Biotype 1A Strains Is Located on the Genomes of Novel Prophages. PMID: 41303648
Cloning, expression and characterization of attachment-invasion locus protein (Ail) of Yersinia enterocolitica and its utilization in rapid detection by immunoassays. PMID: 20002570
Two novel ail-positive biotype 1A strains of Yersinia enterocolitica isolated in China with unequal adhesion and invasion properties. PMID: 25038297
Correction to: Cloning, expression and characterization of attachment-invasion locus protein (Ail) of Yersinia enterocolitica and its utilization in rapid detection by immunoassays. PMID: 41665638
Specific identification of pathogenic Yersinia enterocolitica by monoclonal antibodies generated against recombinant attachment invasion locus (rAil) protein. PMID: 22806848
The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection. PMID: 29751540
Possible use of ail and foxA polymorphisms for detecting pathogenic Yersinia enterocolitica. PMID: 20691098
Characterization of a Yersinia enterocolitica biotype 1A strain harbouring an ail gene. PMID: 21794036
Yersinia spp. in Wild Rodents and Shrews in Finland. PMID: 28332937
Bacterial adhesion and host cell factors leading to effector protein injection by type III secretion system. PMID: 31178419
Prevalence, Genetic Homogeneity, and Antibiotic Resistance of Pathogenic Yersinia enterocolitica Strains Isolated from Slaughtered Pigs in Bulgaria. PMID: 37107078
Ultra-Sensitive and Rapid Detection of Pathogenic Yersinia enterocolitica Based on the CRISPR/Cas12a Nucleic Acid Identification Platform. PMID: 35885403
Parallel independent evolution of pathogenicity within the genus Yersinia. PMID: 24753568
Real-time PCR method for detection of pathogenic Yersinia enterocolitica in food. PMID: 18708521
Comparison of culture, multiplex, and 5' nuclease polymerase chain reaction assays for the rapid detection of Yersinia enterocolitica in swine and pork products. PMID: 11563512
[Detection of Yersinia Enterocolitica Bacteriophage PhiYe-F10 Lysis Spectrum and Analysis of the Relationship between Lysis Ability and Virulence Gene of Yersinia Enterocolitica]. PMID: 27396162
Role of cold climate and freeze-thaw on the survival, transport, and virulence of Yersinia enterocolitica. PMID: 24283700
Application of a convenient DNA extraction method and multiplex PCR for the direct detection of Staphylococcus aureus and Yersinia enterocolitica in milk samples. PMID: 12270272
Prevalence of virulent Yersinia enterocolitica in bulk raw milk and retail cheese in northern-west of Iran. PMID: 22309651
[Evaluation of the usefulness of selected virulence markers for identification of virulent strains of Yersinia enterocolitica strains. III. Chromosome markers of virulence]. PMID: 11107779
A comparison between a PCR method and a conventional culture method for detecting pathogenic Yersinia enterocolitica in food. PMID: 8810057
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