武汉艾必赛生物有限公司推荐Anti-CSFV Glycoprotein E2 Recombinant Antibody (SAA2532) ,精品抗体

链接：https://www.abinscience.cn/product/34/44527.html

名称：Anti-CSFV Glycoprotein E2 Recombinant Antibody (SAA2532)

货号：VK750023

种属反应性：Classical swine fever virus (CSFV)

应用：ELISA

宿主：Mouse

克隆类型：Monoclonal

同种型：VHH-mFc

克隆号：SAA2532

靶标：Autoprotease p20, Capsid protein C, Cysteine protease NS2, E(rns) glycoprotein, EC:2.7.7.48, EC:3.4.21.113, EC:3.4.22.-, EC:3.6.1.15, EC:3.6.4.13, Envelope glycoprotein E1, Envelope glycoprotein E2, Genome polyprotein, N-pro, N-terminal protease, NS2-3, NS4A, NS4B, NS5A, NS5B, Non-structural protein 2, Non-structural protein 2-3, Non-structural protein 3, Non-structural protein 4A, Non-structural protein 4B, Non-structural protein 5A, RNA-directed RNA polymerase, Serine protease NS3, Viroporin p7, gp33, gp44/48, gp55

内毒素水平：< 10 EU/mg

纯度：>95% as determined by SDS-PAGE.

纯化方式：Protein A/G purified from cell culture supernatant.

Accession号：P21530

状态：Liquid

用途范围：仅用于科研

储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

产品介绍：Anti-CSFV Glycoprotein E2 Recombinant Antibody (SAA2532, RUO)｜VK750023 是艾必赛生物（abinScience）推出的小鼠源重组单克隆抗体（VHH-mFc），靶向经典猪瘟病毒（Classical swine fever virus, CSFV）的包膜糖蛋白 E2，可作为 CSFV 血清学检测、E2 抗原 assay 及疫苗/抗体评价的阳性/捕获参照工具。该抗体经 Protein A/G 从细胞培养上清中纯化，纯度 >95%（SDS-PAGE），以液体形式保存在 0.01M PBS, pH 7.4 中；频繁使用 2–8°C，长期建议 -20°C 至 -80°C（自收货日起 ≤12 个月）避反复冻融。推荐应用于 ELISA（1:2000–1:20000）。（RUO，仅限科研/非临床用途）

经典猪瘟病毒（CSFV） 属黄病毒科瘟病毒属，为有囊膜单股正链 RNA 病毒，是猪和野猪高度接触性传染病（CSF）的病原，对全球养猪业危害显著。病毒表面三种囊膜糖蛋白 Erns、E1、E2 共同介导吸附与进入宿主细胞，其中 E2 是最主要的保护性抗原——定位于病毒粒子表面，参与细胞嗜性与入侵，并能诱导中和抗体及免疫保护，因此是 CSFV 诊断试剂、亚单位疫苗与 DIVA 策略的核心靶点。

产品购买联系方式：027-87433958/17302791434

邮箱：info@abinscience.com

参考文献：

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography. PMID: 21124458

The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito. PMID: 37018377

The Alphavirus E2 Membrane-Proximal Domain Impacts Capsid Interaction and Glycoprotein Lattice Formation. PMID: 30463969

DHHC enzymes in alphavirus glycoprotein acylation: A target for broad-spectrum antiviral therapy. PMID: 41223056

P108 and T109 on E2 Glycoprotein Domain I Are Critical for the Adaptation of Classical Swine Fever Virus to Rabbits but Not for Virulence in Pigs. PMID: 32581110

Plant-made E2 glycoprotein single-dose vaccine protects pigs against classical swine fever. PMID: 29993179

Budding of alphaviruses. PMID: 15567491

Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus. PMID: 37768084

Immunogenicity of a secreted, C-terminally truncated, form of bovine viral diarrhea virus E2 glycoprotein as a potential candidate in subunit vaccine development. PMID: 36609424

An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry. PMID: 28031364

Glycoprotein E2 of classical swine fever virus: expression in insect cells and identification as a ribonuclease. PMID: 8178442

Functional analysis of cell surface-expressed hepatitis C virus E2 glycoprotein. PMID: 10400776

Computational identification of a multi-peptide vaccine candidate in E2 glycoprotein against diverse Hepatitis C virus genotypes. PMID: 37194293

Retention and topology of the bovine viral diarrhea virus glycoprotein E2. PMID: 28874234

Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein. PMID: 36913428

The pestivirus E(rns) glycoprotein interacts with E2 in both infected cells and mature virions. PMID: 14554096

Recombinant bovine adenovirus type 3 expressing bovine viral diarrhea virus glycoprotein E2 induces an immune response in cotton rats. PMID: 11112498

Presence of bovine viral diarrhea virus (BVDV) E2 glycoprotein in VSV recombinant particles and induction of neutralizing BVDV antibodies in mice. PMID: 10989181

The envelope glycoprotein E2 is a determinant of cell culture tropism in ruminant pestiviruses. PMID: 12692293

Efficacy of E2 glycoprotein fused to porcine CD154 as a novel chimeric subunit vaccine to prevent classical swine fever virus vertical transmission in pregnant sows. PMID: 28622852

The hypervariable region 1 of the E2 glycoprotein of hepatitis C virus binds to glycosaminoglycans, but this binding does not lead to infection in a pseudotype system. PMID: 15078928

Establishment of an enzyme-linked immunosorbent assay for Getah virus infection in horses using a 20-mer synthetic peptide for the E2 glycoprotein as an antigen. PMID: 31853643

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