链接：https://www.abinscience.cn/product/34/15414.html
名称：Anti-DERP1 Antibody (SAA0622)
别名：Anti-DERP1 Antibody (SAA0622)，DERP1
货号：JN833043
适用物种：Dermatophagoides pteronyssinus (European house dust mite)
寄主物种：Human
形式：Liquid
纯度：>95% as determined by SDS-PAGE
克隆性：Monoclonal
同种型：IgG1
应用：ELISA, WB
UniProt：P08176
靶点：DERP1, Peptidase 1, Allergen Der P I, Major mite fecal allergen Der P 1
用途范围：仅用于科研
储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
产品介绍：Anti-DERP1 Antibody (SAA0622) 是针对屋尘螨主要过敏原蛋白 DERP1 的单克隆抗体。屋尘螨的 DERP1 是一种含 320 个氨基酸、分子量约 35.7kDa 的糖基化硫醇蛋白酶，属于 C1 肽酶家族，具有较强的蛋白水解能力，可破坏呼吸道上皮屏障并引发过敏反应。该抗体适用于 ELISA 和 Western Blot 实验，能够特异性结合 DERP1，可用于检测样本中的 DERP1 蛋白，在过敏性疾病的研究中具有重要应用价值。abinScience产品具有亲和力高，灵敏度高，特异性好，稳定性强等优势。
产品购买联系方式：027-87433958/17302791434
参考文献：
Dermatophagoides Pteronyssinus 1 (DerP1) May Trigger NLRP3-Mediated Corneal Epithelial Cell Pyroptosis by Elevating Interleukin-33 Expression Levels. PMID: 37615401
Derp1-modified dendritic cells attenuate allergic inflammation by regulating the development of T helper type1(Th1)/Th2 cells and regulatory T cells in a murine model of allergic rhinitis. PMID: 28802126
IL-6 mediates olfactory dysfunction in a mouse model of allergic rhinitis. PMID: 38531465
RBCK1 Overexpression Attenuates Inflammation and Mobility of Derp1-Induced Nasal Mucosal Cells by Downregulating NLRP3. PMID: 36702106
Sublingual allergen immunotherapy prevents house dust mite inhalant type 2 immunity through dendritic cell-mediated induction of Foxp3+ regulatory T cells. PMID: 38570140
House dust mite allergen (Derp1 and Blot5) levels in asthmatics' home in Hongkong. PMID: 15506644
Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8. PMID: 40051629
Abnormal purine metabolism in nasal epithelial cells affects allergic rhinitis by regulating Th17/Treg cells. PMID: 39970135
Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model. PMID: 29318623
Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3. PMID: 33556295
Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia. PMID: 38318660
RORα overexpression reduced interleukin-33 expression and prevented mast cell degranulation and inflammation by inducing autophagy in allergic rhinitis. PMID: 37904695
Intranasal immunization with DNA vaccine coexpressing Der p 1 and ubiquitin in an allergic rhinitis mouse model. PMID: 25240330
Interleukin 1β Mediates the Pathogenesis of Nasal Mucosal Epithelial Barrier Dysfunction in Allergic Rhinitis. PMID: 39588138
High Mobility Group Box-1 Protein and Interleukin 33 Expression in Allergic Rhinitis. PMID: 34979505
Higher House Dust Mite-Specific IgE Levels among Chronic Spontaneous Urticaria Patients May Implicate Higher Basophil Reactivity. PMID: 37604140
[Construction of recombinant house dust mite group 1 allergen vaccine and study on immune response induced by nasal immunization]. PMID: 23656812
The CXCR4/miR-125b/FoxP3 axis regulates the function of the epithelial barrier via autophagy in allergic rhinitis. PMID: 32655791
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