链接：https://www.abinscience.cn/product/34/15345.html
名称：Anti-Ganglioside GM3/NeuGcGM3 Antibody (SAA0555)
货号：YP809033
适用物种：General
寄主物种：Mouse
形式：Liquid
纯度：>95% as determined by SDS-PAGE.
克隆性：Monoclonal
同种型：IgG2a
应用：ELISA, WB
靶点：Ganglioside N-glycolyl GM3, N-glycolylneuraminic acid -NeuGc, NGNA-GM3 ganglioside, NeuGcGM3, sialic acid N-glycolylneuraminic acid Neu5Gc
用途范围：仅用于科研
储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
产品介绍：Ganglioside GM3 是 a、b 和 c 系列神经节苷的前体，与表皮生长因子和胰岛素受体等跨膜受体相互作用，通过创造专门的脂质环境调节受体功能。Ganglioside GM3 由 GM3 合成酶合成，可用于高胆固醇血症的研究。该抗体产品能够特异性识别 GM3 和 NeuGcGM3，适用于免疫组化、流式细胞术、免疫沉淀等实验技术，可用于检测样本中的 GM3/NeuGcGM3 表达水平，帮助研究人员在肿瘤生物学、细胞信号转导以及疾病诊断等领域开展研究。abinScience产品具有亲和力高，灵敏度高，特异性好，稳定性强等优势。
产品购买联系方式：027-87433958/17302791434
参考文献：
Ganglioside GM3 Protects Against Abdominal Aortic Aneurysm by Suppressing Ferroptosis. PMID: 38018467
Ganglioside GM3 and Its Role in Cancer. PMID: 29376491
Biology of GM3 Ganglioside. PMID: 29747813
Ganglioside GM3-based anticancer vaccines: Reviewing the mechanism and current strategies. PMID: 38820973
Homeostatic and pathogenic roles of the GM3 ganglioside. PMID: 34125497
GM3(Neu5Gc) ganglioside: an evolution fixed neoantigen for cancer immunotherapy. PMID: 30318083
Ganglioside GM3 deficiency enhances mast cell sensitivity. PMID: 37098812
Ganglioside GM3 as a gatekeeper of obesity-associated insulin resistance: Evidence and mechanisms. PMID: 26434718
Ganglioside GM3 stimulates lipid-protein co-assembly in alpha-synuclein amyloid formation. PMID: 36493587
Ganglioside GM3 and its biological functions. PMID: 19364317
Sialyltransferase Activity Assay for Ganglioside GM3 Synthase. PMID: 36587074
Cell density-dependent membrane distribution of ganglioside GM3 in melanoma cells. PMID: 37249637
GM3 and cancer. PMID: 25613425
Endothelial ganglioside GM3 regulates angiogenesis in solid tumors. PMID: 34216992
Ganglioside GM3 Up-Regulate Chondrogenic Differentiation by Transform Growth Factor Receptors. PMID: 32183071
[Homeostatic and Pathophysiological Regulation of Toll-like Receptor 4 Signaling by GM3 Ganglioside Molecular Species]. PMID: 35228371
Exogenous GM3 ganglioside inhibits atherosclerosis via multiple steps: A potential atheroprotective drug. PMID: 31526872
Sialidase-Resistant Ganglioside GM3 Analogues: Evaluation of Biological Activity. PMID: 36587072
Afterword (Editorial). PMID: 36322334
Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 synthase deficiency variants. PMID: 37676252
Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility. PMID: 27729281
GM3 and diabetes. PMID: 24399479
Monosialyl Ganglioside GM3 Decreases Apolipoprotein B-100 Secretion in Liver Cells. PMID: 28019668
Chemoenzymatic synthesis and biological evaluation of ganglioside GM3 and lyso-GM3 as potential agents for cancer therapy. PMID: 34492428
Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity. PMID: 32378734
Ganglioside GM3 content in skeletal muscles is increased in type 2 but decreased in type 1 diabetes rat models: Implications of glycosphingolipid metabolism in pathophysiology of diabetes. PMID: 28544772
Ganglioside GM3 inhibits the high glucose- and TGF-beta1-induced proliferation of rat glomerular mesangial cells. PMID: 15939439
Ganglioside GM3 induces cumulus cell apoptosis through inhibition of epidermal growth factor receptor-mediated PI3K/AKT signaling pathways during in vitro maturation of pig oocytes. PMID: 28585705
Tumor hypoxia regulates ganglioside GM3 synthase, which contributes to oxidative stress resistance in malignant melanoma. PMID: 32861756
Ganglioside GM3 inhibits the proliferation of cultured keratinocytes. PMID: 8496625
[The regulation of ganglioside GM3 synthesis]. PMID: 22864347
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