名称：Anti-Human CD233/SLC4A1 Antibody (C4201)
Accession号：P02730
货号：HF626107
种属反应性：Human
宿主：Mouse
形式：Liquid
纯度：>95% as determined by SDS-PAGE.
克隆性：Monoclonal
同种型：IgG1, kappa
应用：FCM
靶点：Anion exchange protein 1, Anion exchanger 1, EPB3, CD233, Band 3 anion transport protein, AE 1, DI, AE1, SLC4A1, Solute carrier family 4 member 1
用途范围：仅用于科研
储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
产品介绍：Anti-Human CD233/SLC4A1 Antibody (C4201)是武汉艾必赛生物技术有限公司推出的一款高特异性、经流式验证的小鼠源单克隆抗体。该抗体靶向人阴离子交换蛋白1 (Anion exchange protein 1)，也称为CD233或SLC4A1，该蛋白是红细胞膜上负责氯离子和碳酸氢根离子交换的关键转运蛋白，在维持红细胞结构稳定、气体运输及细胞内pH稳态中起着至关重要的作用。本品克隆号为C4201，通过Protein A/G从细胞培养上清中纯化，纯度超过95%，经严格验证适用于流式细胞术 (FCM)。其出色的特异性与灵敏度，在CD233转染的CHO细胞模型中得到充分证实，是研究溶血性贫血、遗传性球形红细胞增多症等红细胞相关疾病，以及探索细胞膜离子通道功能的可靠工具试剂。
产品购买联系方式：027-87433958/17302791434
邮箱：info@abinscience.com
参考文献：
Identification
of a cross-reacting, monoclonal anti-human CD233 antibody for
identification and sorting of rhesus macaque erythrocytes. PMID:
22170815
Differential
effect of plasma or erythrocyte AGE-ligands of RAGE on expression of
transcripts for receptor isoforms. PMID: 19815443
Clinical
Diagnosis of Red Cell Membrane Disorders: Comparison of Osmotic
Gradient Ektacytometry and Eosin Maleimide (EMA) Fluorescence Test for
Red Cell Band 3 (AE1, SLC4A1) Content for Clinical Diagnosis. PMID:
32636758
Multi-omics
Mendelian randomization integrating GWAS, eQTL and pQTL data revealed
GSTM4 as a potential drug target for migraine. PMID: 39039470
The pathophysiology of distal renal tubular acidosis. PMID: 37016093
A novel variant of SLC4A1 for hereditary spherocytosis in a Chinese family: a case report and systematic review. PMID: 36463227
Mutations and clinical characteristics of dRTA caused by SLC4A1 mutations: Analysis based on published patients. PMID: 36776909
Genotype-phenotype correlation in children with hereditary spherocytosis. PMID: 32436265
Novel Variant of the SLC4A1 Gene Associated with Hereditary Spherocytosis. PMID: 36979763
Organization
and Dynamics of the Red Blood Cell Band 3 Anion Exchanger SLC4A1:
Insights From Molecular Dynamics Simulations. PMID: 35283786
Genome-Wide
Association for HbA1c in Malay Identified Deletion on SLC4A1 that
Influences HbA1c Independent of Glycemia. PMID: 32936915
Band 3, the human red cell chloride/bicarbonate anion exchanger (AE1, SLC4A1), in a structural context. PMID: 27058983
Comprehensive Genetic Analysis Reveals Complexity of Monogenic Urinary Stone Disease. PMID: 34805638
Activation
of lncRNA lnc-SLC4A1-1 induced by H3K27 acetylation promotes the
development of breast cancer via activating CXCL8 and NF-kB pathway.
PMID: 31556319
A novel SLC4A1 splice variant (c.2655+2_2655+3 del) in hereditary spherocytosis. PMID: 33470548
Unveiling the role of RPS17 and SLC4A1 in diamond-Blackfan Anemia: A zebrafish-based study. PMID: 40015014
Physcion
8-O-beta-glucopyranoside exerts carcinostasis ability in Ishikawa cells
via regulating lnc-SLC4A1-1/H3K27ac/NF-kappaB pathway. PMID: 32635979
A novel SLC4A1 mutation in a child with hereditary spherocytosis and distal renal tubular acidosis. PMID: 35441494
Genotypic
analysis of SLC4A1 A858D mutation in Indian population associated with
distal renal tubular Acidosis (dRTA) coupled with hemolytic anemia.
PMID: 33068675
The hereditary stomatocytoses. PMID: 19644134
详情请咨询 abinScience 亚洲区官方子公司 —— 武汉艾必赛生物技术有限公司
官方网址：【中文】https://www.abinscience.cn
武汉艾必赛生物技术有限公司成立于 2023 年，是 abinScience 在亚洲地区设立的官方全资子公司，全面负责 abinScience 品牌在亚太市场的科研试剂推广、销售及技术支持工作。
依托严格的产品研发体系和国际化的质量管理标准，武汉艾必赛与 AtaGenix、ProteoGenix 等知名品牌保持长期战略合作，现已构建起涵盖抗体、重组蛋白、工具酶、试剂盒、实验耗材在内的多品类供应体系，面向区域内科研机构、高校实验室与生物医药企业，提供稳定、高效、可信赖的产品与服务。
核心业务覆盖：
? 抗体产品（单抗、多抗、重组抗体等）
? 蛋白与多肽试剂（标签蛋白、功能蛋白等）
? 分子与细胞实验相关耗材
? 定制化研发服务（蛋白表达、抗体定制、亲和力成熟等）
? 科研供应链整合与项目配套支持
武汉艾必赛始终秉持“Empowering Bioscience Discovery”的理念，为亚太地区的生命科学研究持续注入高质量动能。
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